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It has been my privilege to work with over 21,262 men over the past years.
And I am just a lowly health researcher.
One of the most common issues that these brave men face is problems getting erections.
Most of them have tried Viagra, or Cialis, or Levitra — sometimes all of them.
And these men generally come to one of two conclusions.
Either they don’t like the side effects and find that Viagra is harmful.
Or, more often, the men find that the drugs have quit working.
The reality is that it’s very difficult to find out what percentage of men find that these drugs stop working.
But I think that the estimates of 50% are quite accurate.
In the experience of the thousands of men who have sent emails, the problem gets progressively worse and worse.
But it’s difficult to find any studies that show this.
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The problem is that big drug companies funded the only studies on these drugs.
But this study gets closer to the truth than most of them.
The study looks at sildenafil, which is another word for Viagra.
But because of the way that sildenafil works, what applies to it will apply to all of the similar PDE5 inhibitors drugs.
So although this study focuses on Viagra, you can safely assume it applies to Cialis and Levitra.
When they started, 74% of the men in this study were able to get erections that were satisfactory enough for intercourse.
But overall, 50% of the time, within a year, the drugs stopped working.
Reduction in efficacy ranged from 15% to 50% (mean 36 ± 12%) and the time to loss of efficacy ranged from 1 to 18 months (mean 11 ± 5).
Of the 82 patients in the second surgery, 39 (48%) stopped using sildenafil.
14 (50%) patients discontinued sildenafil because of the loss of efficacy.
Now let me tell you why I think the results are worse than this study shows.
At the time of this study, the men taking these drugs had other major health issues.
It was those other health issues that caused the men’s erectile issues and sent the men looking for help.
Nowadays, 16 years or 18 years later, men are taking these drugs for a new reason.
They are looking for the solution to desensitization-caused erectile dysfunction rather than health-caused erectile dysfunction.
And these drugs tend to accelerate the downhill slide of desensitization into a total lack of feeling.
This study calls it the tachyphylaxis effect.
The tachyphylaxis effect is defined as:
rapidly diminishing response to successive doses of a drug, rendering it less effective. The effect is common with drugs acting on the nervous system.
I call it desensitization.
It’s a much greater problem than this study indicates.
And the problem is that these drugs do not only make a lot of things worse.
They also cause a man to feel less and less.
And the problem gets worse more quickly than it would otherwise.
The drugs result in eventual total erectile dysfunction in many men.
The study doesn’t show how the 50% of men who quit are doing today.
But I believe many of them could be successfully treated for desensitization using other approaches.
And they should avoid these drugs altogether.
http://www.sciencedirect.com/science/article/pii/S0022534705658661
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