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Harvard research: hidden benefit of raising your bile acid
Have you ever heard of bile?
It sounds super gross, but it’s very important to how your body functions.
Bile is produced in the liver, and it helps our bodies digest food and break down fatty acids.
Bile production is one of the reasons it’s important to pay attention to liver health.
Bile acids made by the liver have long been known for their critical role in helping to absorb the food we ingest.
New research is showing that bile acids play more roles than just digestion.
They can also help our bodies to bolster immunity.
In a study from the Harvard Medical School, researchers looked at bile acids.
They studied how bile acids interact with the gut microbiome to influence gut immunity and inflammation.
This is cutting edge research because it focuses on complex processes within our body…
And how the trillions of bacteria we carry around affect those processes.
These fat- and vitamin-dissolving substances are also important players in gut immunity and inflammation because they regulate the activity of key immune cells linked to a range of inflammatory bowel conditions, such as ulcerative colitis and Crohn’s disease.
The bile acids work with specific bacteria in the gut to affect the way the immune response works.
If your gut is healthy, then the bile works together with the bacteria in your gut to regulate your immune response.
The studies identify three bile acid metabolites and corresponding bacterial genes that produce molecules that affect the activity of inflammation-regulating immune cells. The work also demonstrates that the presence and activity of these bacteria and the immune molecules they produce are notably reduced in patients with inflammatory bowel disease (IBD).
Without the bacteria, the bile acids can’t do their work and people with IBD don’t have as much of the “right” bacteria in their guts.
Then the inflammation and immune response gets out of whack.
People who have lower levels of the bacteria they need include folks with Crohn’s disease and colitis.
Furthermore, they show that intestinal samples from patients with conditions such as ulcerative colitis or Crohn’s disease have markedly lower levels of both the anti-inflammatory molecules and the bacterial genes responsible for their production.
Of course, the Big Pharma companies are looking for therapeutics that can help to fix this bacterial problem in folks with serious gut inflammation.
The findings bring scientists a step closer to developing small-molecule treatments and live bacterial therapeutics that regulate intestinal inflammation.
It’s expected, because Big Pharma seems to take ANY opportunity to monetize a disease – even if there are better solutions to fixing things.
If you have a disease in the IBD family, you know how painful and potentially embarrassing it can be.
I completely understand the research…
But I think that it can take us in directions where we can help our bodies heal themselves.
One of the things that I really pay attention to in my work is gut health.
The gut is the key to so many different health conditions because it plays a serious role in maintaining our immune systems.
But it’s not JUST the gut.
As you can see from this research, the bile produced in the liver interacts with the gut in a way that can either help us have great health…
…or cause major health conditions.
When you are trying to live a robustly healthy life, then it’s important to pay attention to your body as a system.
That’s where good health comes from.
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