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There are many millions of men and women suffering from chronic pain.

And a lot of these people are taking opiates of various kinds.

They’re taking morphine, codeine, hydrocodone, oxycodone and all sorts of other drugs.

They use them as back pain painkillers.

So here is a very elaborate and well-done study.

It shows that these opiates can actually double or triple the pain that you perceive when you’re taking them.

And it shows that recovering from this double or triple whammy of pain can take WEEKS.

The effects last even after you stop taking the opiates!!!

The study looked at morphine, but the actual findings will apply to any opiate drug including — the synthetic opiates.

So if you’re taking any type of painkiller, you should be aware of the study.

As they say in the study:

A brief course of morphine treatment, administered upon expression of neuropathic pain, drives persistent sensitization for months after cessation of morphine.

So why does the pain double or triple?

And why does the pain continue even after stopping the opiates?

They call this morphine-induced persistent sensitization.

One of the symptoms is called allodynia.

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Allodynia is a feeling of pain or discomfort related to this sensitization.

It may feel like heat, and it may be in a completely different part of the body than where the original pain was.

Opioids exaggerate pain in preclinical models of peripheral inflammation and surgery as well as clinically.

But there’s also much more to the problem.

The way that the opiates work increases harmful inflammation in the body.

And the process speeds up aging.

Secondly, opioids superimposed on CNS neuro-inflammation may have far-ranging consequences beyond pain.

For example, opioids may also serve as a second hit for glia primed by aging or inflammation/trauma and may lead to cognitive decline in the elderly.

This double hit is the worst of it.

These opiate painkillers increase inflammation in the brain and the nervous system.

But there may be some new hope for this issue.

The old antibiotic called minocycline may lower this inflammation dramatically.

It looks like it’s a powerful tool against the damage of these painkiller medications.

Minocycline inhibits microglia activation, nitric oxide (NO) production, and the release of pro-inflammatory cytokines and chemokines.

In fact, recent evidence suggests that minocycline may attenuate the neuroinflammatory effects of opioids.

Yale University is conducting these clinical trials.

They will hopefully show how minocycline can vastly lower inflammation caused by opiate painkillers.

In the meantime, many people have found it very effective to get a minocycline prescription from the doctor.

They say that sometimes even one-half of a 100 mg tablet taken daily can help a great deal.

Make sure that you talk to your doctor first, as Minocycline is a prescription antibiotic.

And like any medication, it has some side effects and risks of its own.

It’s definitely advisable to avoid these opiates as much as possible.

Now, I have posted how pretreatment before pain with opiates can actually help/resulting pain afterward.

It’s true, but it is also true that taking opiates after the pain begins can make the pain much worse and last much longer.

So, ideally you should pretreat before an expected pain.

Then you won’t need to take the opiates after the pain — such as after surgery.

And, if you are on opiates now, you may want to consider talking your doctor about minocycline.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.