And a gene that lets men process serotonin differently…VERY big results…
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Serotonin — is it as good as they say, or is it bad?
Big Pharma markets Serotonin as “The Happy Hormone” — but this is a dangerous myth.
And it’s a myth that is very useful to Big Pharma corporations who can patent molecules which increase serotonin…
…then sell those as “antidepressants” making billions of dollars in the process.
We know now that much of the research used to sell those substances was flat out fraudulent — some was simply based on false assumptions.
What is clear is that serotonin does NOT make people happy.
In fact, it causes depression, anxiety…and can increase violent behavior.
This human research was carried out at the Karolinska Institutet in Stockholm, Sweden. The paper was published in European Neuropsychopharmacology.
The paper looked at violence in people using SSRIs.
SSRIs are a type of “antidepressant” treatment. The acronym stands for selective serotonin reuptake inhibitor.
The treatments were designed to keep levels of serotonin higher in certain parts of the brain — to “inhibit uptake.”
Swedes keep meticulous records on matters of health. There is a national registry for regulated treatments which tracks substance use for every Swedish citizen.
These records can be matched up with detailed Swedish crime databases.
By doing this, the researchers were able to look at the relationship between taking an SSRI (serotonin booster) and the likelihood of being convicted of a violent crime.
“We identified individuals ‘given’ SSRIs between 2006 and 2013. The outcome was violent crime conviction.”
Younger people were 10 to 20% more likely to be convicted of a violent crime if they were taking these serotonin-boosting treatments.
“We found statistically significantly elevated hazard ratios for violent crime conviction in 15-34 year olds taking SSRIs.”
The increase in violent crime was much smaller in older SSRI users.
But then, most violent crime is done by younger people.
Older folks don’t act out their rage so effectively.
When they looked at violent crime convictions in the same individual on or off the treatment, the numbers were even higher.
The same person was up to 35% more likely to be convicted of a violent crime when they were taking an SSRI.
The increase in violent crime rates on treatments persisted for 12 weeks after the treatments were stopped.
“The increase in violent crime conviction was elevated throughout treatment and for up to 12 weeks post discontinuation.”
The study shows a clear relationship between violent crime and these treatments.
“These results indicate that there may be an increased risk of violent crime during SSRI treatment which may persist across all age groups and after treatment discontinuation.”
And there is also animal research going back decades showing increases in aggression in animals with higher serotonin.
In humans, we have numerous other lines of evidence showing that high serotonin is involved in aggression and violence.
Have you ever heard of The Warrior Gene?
It was a big thing in the media a few years ago.
The warrior gene is a slight alteration in an enzyme which processes serotonin.
People with The Warrior Gene are not as efficient at destroying serotonin — they have higher serotonin.
People with the warrior gene are, as you may have guessed, more violent.
The warrior gene means people have lower MAOA — MAOA destroys serotonin.
“MAOA is involved in the breakdown of serotonin and can alter behaviour. A mutation to the gene that is involved in the process of promoting or inhibiting MAO enzymes could make a person more prone to aggression.”
In fact, here’s an extreme but true story. Back in 2006, Bradley Waldroup shot a woman eight times and sliced her head open.
He was charged with murder and tried in 2009.
The jury convicted him of a far lesser crime of second degree manslaughter after hearing evidence that Mr. Waldroup has the “warrior gene.”
A gene that amplifies negative effects of serotonin through an aberration in how his body handles MAO, increasing serotonin.
I think it best to lower serotonin rather than to boost it. It gives me a much calmer feeling…and it is better for the body
Coming off of any SSRI treatments can be very tricky — don’t do it cold turkey.
Always speak to your healthcare provider about changing or reducing treatments.
But I would try to get off those if you can.
Wellbutrin may be an option to discuss, and the older tricyclic antidepressants are a great replacement…
And here is a list to discuss with your doctor:
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(Don’t be put off that these are “old treatments” — they are probably much better than the newer SSRIs as we’ve seen…)
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