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Saffron may cure depression and anxiety in men
Saffron, a spice, comes from the saffron crocus.
Small filaments grow out from the flower.
These filaments have been used in cooking and traditional medicines for over a thousand years.
Saffron contains over 100 different chemical compounds with many biological effects.
And a number of studies show that saffron is a powerful antidepressant.
A recent human study using saffron extract lowered tension, depression, confusion, and fatigue.
This research took place at the University of Queensland in Australia. The Journal of Complementary Therapies in Medicine published the results.
Phytotherapy is the scientific study of plant medicine.
“In recent years phytotherapy has been explored as a source for alternative treatments for mood disorders.”
This study used an extract of saffron, standardized for two of its main active compounds.
“One potential candidate for mood disorders is saffron, whose main bioactive components are crocins and safranal.”
The study looked at saffron’s effect on mood, stress, anxiety, and sleep.
“We investigated saffron extract for improving mood, stress, anxiety, and sleep quality in healthy adults.”
The researchers recruited over 100 people with low mood.
“128 participants with low mood but not diagnosed with depression, were given affron® at 28 mg/day, 22 mg/day, or a placebo treatment.”
The high-quality, randomized, double-blind, placebo-controlled trial lasted for four weeks.
They used a number of industry-standard questionnaires prior to and at the end of the study.
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The study found higher-dose saffron extract effective in boosting mood and lowering stress.
“Analysis indicated a significant decrease in negative mood and symptoms related to stress and anxiety at a 28 mg/day dose.”
And the participants didn’t report any side effects during the course of the study.
“Affron® increased mood, reduced anxiety, and managed stress without side effects, offering a natural alternative to standard treatments.”
The researchers believe saffron could be a safer treatment for low mood.
“Given the excellent safety profile saffron and the issues with antidepressants there is a strong case for using saffron in management of low mood states.”
This is not the first study showing the mood-boosting effect of saffron.
A number of studies have been carried out in Iran. This one took place at the Tehran University of Medical Sciences.
“Saffron is used for depression in Persian traditional medicine.”
These researchers investigated the effect of whole saffron in mild-to-moderate depression.
“We assessed the efficacy of saffron in mild to moderate depression in a six week double-blind, placebo-controlled, randomized trial.”
The study included 40 participants diagnosed with major depression.
The scientists randomly assigned the participants to 30 mg saffron twice a day or placebo.
“Patients were randomly assigned to receive a capsule of saffron (30 mg) or a capsule of placebo for a six-week study.”
People given saffron had much lower depression rating scores at the end of the trial.
“At six weeks, Crocus sativus produced a significantly better outcome on the Hamilton depression rating scale than the placebo.”
And this trial, too, found that saffron had no side effects.
“There were no significant differences in the two groups in terms of the observed side effects.”
So saffron seems to be effective in boosting mood and treating moderate depression.
“The results of this study indicate the efficacy of saffron in the treatment of mild to moderate depression. A large-scale trial is justified.”
You should always consult a healthcare professional about treating and diagnosing health problems.
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- affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial
https://www.sciencedirect.com/science/article/pii/S0965229917300821?via%3Dihub - Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial.
https://www.ncbi.nlm.nih.gov/pubmed/15852492
- The effects of Crocus sativus (saffron) and its constituents on nervous system: A review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599112/ - 11 Impressive Health Benefits of Saffron
https://www.healthline.com/nutrition/saffron