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If you’re considering testosterone replacement therapy, you need to do some serious research first.

And we have more research for you today about testosterone therapy risks.

If you have a testosterone deficiency, there’s a chance your doctor will advise you to try testosterone replacement.

Doctors use testosterone replacement therapy (TRT) to treat male hypogonadism.

Hypogonadism means that your testicles are not producing high enough levels of testosterone.

It’s a general diagnosis — there can be many reasons for it.

And they’ve used TRT to treat it for more than 60 years.

In testosterone replacement therapy, patients receive extra testosterone delivered by topical gels, pills, or intramuscular injections.

Typically, doctors recommend TRT after a man tells his doctor about issues he’s having in the bedroom.

Most symptoms of testosterone deficiency become most obvious to the individual man by the time he is about 50.
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He may have a reduced libido, fewer spontaneous erections, or notice that his testicles appear smaller.

A patient may notice a loss of body hair, and he may need to shave less frequently.

Another effect of low T is that the man may experience breast discomfort or gynecomastia.

Patients report decreased muscle mass, less strength, and tests might show decreased bone density.

He might even have hot flushes!

There’s a reason why hypogonadism has the nickname “male menopause.”

And the problem is pretty common.

A large number of 50-year-old men have testosterone levels that are below what is considered normal.

About 15-25% of men over the age of 50 years experience low serum testosterone levels.

And these levels are well below the threshold considered normal for men between 20 and 40 years of age.

The good news is that lots of research studies prove that supplemental testosterone helps older men with these symptoms.

It gives these men back that feeling of well-being they had when they were younger.

So, it’s now common practice to treat men with age-related testosterone deficiency.

The most common method of delivering testosterone supplements is still shots.

The patches are less popular because many of them cause negative skin reactions.

And many men benefit from whichever method they use.

But there’s a cost to testosterone replacement therapy, adn there are side effects of testosterone injections, patches, and pills.

Overall health suffers.

In this study, researchers compared men aged 45 and older receiving TRT treatments with others receiving a placebo.

651 men received testosterone, while 433 received the placebo.

When they compared the results, they found that having too much testosterone is also a problem.

They noticed it related to an increased number of prostate events.

The prostate cancer rates and PSA levels increased, and they needed more biopsies in the testosterone treated group.

Men treated with testosterone were 1.8 times more likely to develop a prostate-related event.

But remember, yesterday we talked about how low testosterone increased cancer rates.

And high PSA rates also linked to increased cancer rates.

So the problem may not be the testosterone itself, but the PSA level increases.

But testosterone isn’t completely off the hook.

Men on testosterone therapy experience other issues.

For example, men on testosterone therapy, they have an increased rate of hair loss.

Dihydrotestosterone (DHT) another steroid hormone in the body made from testosterone.

But having too much DHT leads to hair loss.

It shrinks hair follicles, which often leads to shedding and increased rates of male pattern baldness.

And getting more testosterone increases the levels of DHT, so you go bald faster.

Testosterone therapy also causes erythrocytosis.

Without a medical biology lesson, think of erythrocytosis as having way too many red blood cells.

The blood needs a balance of its components to circulate and transfer nutrients and oxygen properly.

And when you have too many red blood cells, it throws the balance off by making your blood thicker.

Blood should contain approximately 45% red blood cells.

But men on testosterone therapy are four times more likely to have a red blood cell concentration higher than 50%.

Higher red blood cell concentrations make your blood thicker and cause decreased blood flow.

Which leads to an increased chance of the heart not being able to pump enough blood.

And it can lead to heart disease deaths.

Some studies associate it with hardened arteries, stroke, and other forms of heart disease.

In fact, men on testosterone replacement therapy were twice as likely to suffer a heart attack!

The men observed in this study had a two times increase in heart attacks as men receiving a placebo.

Testosterone therapy also increases cholesterol issues.

You probably know that we have two types of cholesterol — HDL and LDL.

We call HDL the good cholesterol.

It works by helping to get rid of LDL (bad cholesterol) by sending to the liver.

And the liver eventually eliminates the LDL cholesterol from the body.

But testosterone therapy is associated with inhibiting HDL production.

Which then allows LDL levels to build up.

That buildup contributes to the lipoproteins snagging the LDL cholesterol and pasting it to your artery walls.

Eventually, it builds up to block arteries.

This blockage stops blood flow like a dam and keeps enough blood from reaching the heart, brain, and other major organs.

So, what does this mean for you?

First, don’t jump at testosterone replacement as a fix until you know all the facts.

TRT is an appealing concept.

Who wouldn’t want to regain the vigor and energy they had in the past??

But you shouldn’t enter it lightly.

You need to monitor it carefully to prevent what could be catastrophic consequences.

Instead, you might want to try increasing your testosterone through natural methods first.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.