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This actually protects your testosterone as you age…
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This study is freaking doctors out
This is huge…”The Censored One” study that Big Pharma corporations pray you never see.
I’m busting open The Censored One and showing everything to you here, deciphered and uncensored.
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Is this more important than testosterone?
Testosterone tends to decline with age.
And declining testosterone is associated with loss of energy and activity, even when it is independent of aging.
Dopamine is a neurotransmitter that is important for motivation and vitality.
And, like testosterone, dopamine decreases with age.
It also seems that a decrease in dopamine may be involved in some types of dementia, such as Alzheimer’s disease.
A new study shows that increasing testosterone leads to increased activity and vitality by boosting dopamine.
This rodent study was published in the journal Nature.
There are a number of ways to measure testosterone. This study measured free testosterone.
This study set out to find out why a decrease in testosterone caused by castration leads to decreased activity in the lab animals.
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Previous experiments showed that castration led to a decrease in physical activity in animals.
“Castration in rodents results in decreased physical activity.”
These researchers conducted experiments on three different types of mice in order to identify the mechanisms of this phenomenon.
They determined “activity” by how much the animals used a running wheel.
“We studied voluntary wheel-running behavior in three different mouse models of androgen deficiency.”
One group of mice were castrated mice.
The mice in another group were bred to have no androgen receptors. This means that androgens such as testosterone could not have much effect on them.
The third group of mice had a genetic mutation in sex hormone binding globulin (SHBG). This means they had very low free testosterone.
Through these experiments, the scientists were able to prove that free testosterone stimulated an increase in physical activity in the animals.
“Our results clearly show a fast and dramatic action of testosterone stimulating wheel running.”
Testosterone does have an effect on muscles (it can increase muscle mass)…
However, the effect on the activity levels of the mice was not due to the effect of testosterone on their muscles.
“The dramatic action of testosterone stimulating wheel running is not explained by its action on muscle.”
Scientists conducted a number of experiments using dopamine agonists.
These compounds increase the activity of the neurotransmitter dopamine (as I said above, dopamine is important for motivation and vitality).
And the study found that free testosterone affects sensitivity to dopamine.
“Both gene expression and functional studies indicate that testosterone modulates the insensitivity to dopamine agonists.”
The researchers also investigated the effects of dopamine antagonists.
Antagonists block the effect of dopamine – they are the opposite of agonists.
When the scientists blocked dopamine in the mice, they found that the increase in activity caused by testosterone was also blocked.
So this showed that dopamine mediates the effect that testosterone has on energy and vitality.
“The restoration of wheel running by testosterone is inhibited by treatment with dopamine antagonists.”
The study showed (for the first time) that free testosterone stimulates activity through dopaminergic pathways.
“These findings reveal that free testosterone stimulates physical activity behavior in male mice by acting on dopamine.”
Other studies have indicated that the loss of dopamine and/or dopamine receptors could be involved in brain aging and in dementias such as Alzheimer’s disease.
Though some still dispute this theory, these results could lead to a treatment for aging and dementia through testosterone supplementation.
A review article published in the journal Ageing Neuroscience looked at some of the correlations between dopamine loss, dementia, and aging.
Dopamine’s effects decrease in the brain throughout the aging process in a number of ways.
“Decreased release of dopamine and reduced dopamine receptor expression in the brain are commonly observed in aging.”
Many scientists have shown associations between the loss of energy and motivation and the loss of dopaminergic function.
“…The occurrence of apathy – a negative prognostic sign in both the elderly and Alzheimer’s – is suggested to be the consequence of the impairment of dopamine transmission observed during normal aging as well.”
So there you go. Loss of dopaminergic function is associated with cognitive decline.
“The earlier the impairment of the dopamine system occurs, the faster the cognitive decline goes.”
Perhaps taking measures to protect testosterone levels during the aging process could prevent dementia.
Another possibility is that testosterone supplementation may be a useful treatment.
This whole issue needs more research though.
However, if you are going to do testosterone supplementation, you must do it very carefully and under medical supervision.
That’s because improper dosing of testosterone can lead to a lot of damage because it can increase estrogen.
You should see a healthcare professional about hormones or dementia.
—-Important Message—-
30% testosterone boost in the bathroom?
I use this in the bathroom before I join her in the bedroom for sex.
Hey, it’s Matt Cook and I want to give you this amazing tip that ensures your sexual performance with your wife, your girlfriend, or a girl you just met.
It involves a simple trick that you do in the bathroom…
…it only takes seconds and your testosterone shoots up 30%.
It’s exactly like Clark Kent entering a phone booth and coming out as Superman.
Imagine yourself entering the bathroom with anxiety and a limp penis – and coming out with high T, confidence, and a raging erection
It’s all because of this simple trick that only takes seconds…
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