I call this food the “stroke maker” – avoid it

July 3, 2019 Matt Cook Blood Pressure, Stroke, Vitamin C 0

I call this food the “stroke maker” -- avoid it

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Here’s the food to avoid… For instance, Tokelauan Islanders consume 60% of their energy from an alternative natural food – and they don’t have ANY cardiovascular disease or stroke… 

Tokelauan Islanders

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I call this food the “stroke maker” – AVOID IT

I want to talk about foods to avoid, and foods to eat that prevent heart disease. Starting with stroke.

Stroke is defined as a lack of blood flow often caused by a thrombus, or blood clot.

Common explanations for this can be read online, but they’re usually just a litany of risk factors – none of which are true causes. 

The inclusion of so many risk factors makes for a false sense of complexity…

It also gives the impression that efforts at prevention are impractical and futile.

“The main risk factor for stroke is high blood pressure. Other risk factors include tobacco smoking, obesity, high blood cholesterol, diabetes mellitus, a previous TIA, and atrial fibrillation.” —Wikipedia

This mythology is probably intended to protect the incomes of cardiologists and pharmacologists…

And it obfuscates the true causes while making drugs and surgery seem to be the only option. 

Yet epidemiological, clinical, and postmortem studies since the 1970s show that it’s surprisingly simple to prevent. 

All a person truly needs to do, really, is avoid omega-6 fatty acids and make sure to consume enough vitamin C. 

This is because linoleic acid, an omega-6 fatty acid, turns into a molecule within the body that strongly induces platelet aggregation. 

This molecule is called thromboxane A2 (TXA2), and it’s so notorious for inducing thrombi that it had been named for it. 

Molecular mechanism of thromboxane A₂-induced platelet aggregation."

TXA2 is technically a prostaglandin. And, as such, it is synthesized by cyclooxygenase enzymes. 

The inhibition of TXA2 is why aspirin, even in low doses, powerfully inhibits thrombi and stroke. 

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All cyclooxygenase inhibitors will inhibit the formation of TXA2 – and even natural salicin from willow bark (the ancient version of aspirin) will do it.

And yet, the less linoleic acid a person eats, the less salicylates they’ll need. 

Salicylates will inhibit prostaglandins, which is great. But they do nothing to lower leukotrienes. 

Prostaglandins and leukotrienes, both part of the eicosanoid family of molecules, are associated with inflammation.

Avoiding omega-6 fatty acids inhibits all dangerous eicosanoids. 

Since the 1970s, we have clear evidence that avoiding omega-6 fatty acids will make a person stroke-proof… 

…and that strokes have little to do with things like cholesterol, smoking, obesity, or high blood pressure. 

One reason we know this is because the Greenland Inuit eat tons of cholesterol, protein, and fat… And they tend to obesity…

Yet they have no cardiovascular disease to speak of:

Plasma lipids and lipoproteins in Greenlandic west coast Eskimos.

Bang and Dyerberg spent over a decade studying cardiovascular disease and lipids in the Greenland Inuit population and published over a dozen articles on the subject.

As a result, we know more about the lipid composition of Inuit blood than any other native population.

The Inuit made for such an interesting population to study because, despite their all-meat diet, they experience practically no ischemic cardiovascular events.

“During the 5- year period of 1963-67 only three cases of atherosclerotic heart disease were registered, and not a single case of diabetes mellitus.”

And this obviously has nothing to do with cholesterol: They consume more cholesterol than their Danish neighbors and have similar blood cholesterol levels.

So cholesterol is just a red herring, a harmless bystander often found in pathological arterial segments that had nothing to do with causing them. 

Whale, beef, and seal meat all contain similar amounts of cholesterol. 

And, despite consuming over one pound per person per day of sea animals, the blood cholesterol levels of Inuit is no higher than that of Danes. 

The more cholesterol we consume in our diet, the less of it our body makes. 

Haemostatic function and platelet polyunsaturated fatty acids in Eskimos."

Their serum cholesterol is actually a bit less.

And that is simply a physical property of cholesterol being slightly more soluble in saturated fatty acids than in omega-3 oils. 

Yet saturated fatty acids won’t cause cardiovascular disease either…

The Tokelauan Islanders (off New Zealand) consume 60% of their energy as coconuts and they don’t have any cardiovascular disease either. 

There are actually very few omega-6 fatty acids produced at the equator, and even less can be found in seafood. 

Omega-6 fatty acids are a product of yeast, fungi, helminths, and seeds from temperate regions – including the animals that eat those seeds. 

We humans don’t make omega-6 lipids in our bodies – nor do we need them. 

“Reported observations in some of these island populations have shown that blood pressures are low with little increase with age – and coronary heart disease and strokes are uncommon events.”

So what is the difference? 

Why don’t the Inuit get cardiovascular disease despite eating an all-meat, high-fat, high-cholesterol, and all-omega-3 diet? 

Why don’t the Tokelauans get cardiovascular disease on their diet that is extremely high in saturated fatty acids? The highest in the world, actually…

The reason is surprisingly simple: Neither population consumes any significant amount of omega-6 fatty acids. 

TXA2 can only be made through arachidonic acid, an elongation product of linoleic acid – the ubiquitous omega-6 seed oil. 

Both populations also consume adequate amounts of ascorbic acid (vitamin C), a vitamin that is necessary to maintain the integrity of arterial walls. 

The main protein that blood vessels consist of is collagen – and vitamin C has been shown at 100 micrometers to induce procollagen synthesis fourfold. 

Without vitamin C, the blood vessels cannot contain the pressure. And plaques will form as a defensive measure. 

We also need vitamin C to physically cross-link collagen after it’s laid down. Perhaps that’s why its presence signals procollagen synthesis. 

There are really three main forms of “cardiovascular disease” when it’s defined so broadly.

But all of them share only two fundamental causes: omega-6 fatty acids and lack of vitamin C. 

“In ethnographic descriptions of Eskimos, an enhanced bleeding tendency has often been noted as a peculiarity of unknown cause, as scurvy nearly always could be ruled out.”

The Inuit and the Tokelauans still make thromboxanes in their bodies, despite having mere traces of omega-6 fatty acids in their diets

The ones they do produce are of the slightly different omega-3 type. 

These native populations instead have eicosapentaenoic acid as their main 20-carbon lipid… 

And, under the action of cyclooxygenase, that forms a prostaglandin with essentially no platelet-aggregating ability. 

This is called thromboxane A3 (TXA3). 

TXA3 is what you’d expect, instead of TXA2, after avoiding omega-6 fatty acids for a while.

And the difference between the two lipid classes in this regard has been scientifically demonstrated…

You can see the results of platelet aggregometry tests below. 

This technique uses light transmittance to gauge platelet aggregability…

It works because clumped platelets precipitate thereby allowing more light to pass through the solution: 

Platelet aggregation induces by arachidonic (A and eicosapenatenoic acid (B)
In this illustration, arachidonic acid caused a powerful platelet clumping response (A). 

But eicosapentaenoic acid did nothing, despite the higher concentrations that were used (B). 

Even when stimulated by ADP – a powerful aggregating agent – the platelets co-cultured with eicosapentaenoic acid didn’t aggregate nearly as thoroughly as those with arachidonic acid (C). 

The presence of omega-3 and the lack of omega-6 fatty acids is why the Greenland Inuit have practically zero strokes and heart attacks. 

Since the Inuit have nothing to inhibit besides an aggregation inhibitor, aspirin actually slightly decreases bleeding time in that population. 

Seriously, it really does:

The presence of omega-3 and the lack of omega-6 fatty acids is why the Greenland Inuit have practically zero strokes and heart attacks. 

Some people advocate taking omega-3 oils to combat the omega-6 fatty acids we normally consume. 

Why taking omega-3 oils can be dangerous…

Eating DHA (docosahexaenoic acid, which comes from cold-water ocean animals) – or just polyunsaturated fatty acids in general – can lead to an accelerated buildup of lipofuscin, the “age pigment.” 

This material consists of proteins cross-linked by reactive fragments of lipid peroxidation… And that is catalyzed by free iron.

We can see this as “age spots” on people’s skin — big dark spots that increase with age for those who have high iron and high PUFA consumption, especially fish oil.

Lipofuscin is found in heart after a fish oil diet, and is not found in low-fat controls

Even if a person avoids dying of some terrible disease, they’ll likely die of lipofuscin. 

Besides being a cosmetic issue, lipofuscin progressively accumulates in neurons until there’s little space left for metabolic activity.

In some centenarians, lipofuscin occupies 75% of the volume of neurons, the cell type that accumulates the most of it because they rarely divide.

Cancer and cardiovascular disease kill most Americans, yet lipofuscin will eventually get everybody. 

This inclusion body is informally called the “age pigment” for good reason.

So that’s a good reason for avoiding all polyunsaturated fatty acids (PUFAs), besides the trace amounts found in nearly all foods of course. 

Beef, dairy, vegetables, and fruit are safer foods to consume because they have the smallest amounts of unavoidable PUFAs. 

Most animals, such as pigs and chickens, incorporate the lipids they consume directly into their bodies. 

But cows saturate nearly all lipids in their digestive tract. 

This is why beef and cheese contain essentially all saturated fatty acids, and grass-fed animals should have an even better omega-3/omega-6 ratio. 

And macadamia nuts and coconut are practically the only two PUFA-free nuts. 

Vitamin E also prevents lipofuscin by inhibiting lipid peroxidation.

And avoiding wheat products with free iron should inhibit it further. 

Another natural product that inhibits aggregation is bromelain, an acid-stable protease found in pineapple… Bromelain survives digestion and is absorbed with full activity. 

Bromelain has also been shown to inhibit platelet aggregation by proteolyzing adhesive proteins such as fibrin.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.
Daily Medical Discoveries has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. To continue reading about stroke and other topics that pertain to men, click here. If you’d like further information, feel free to check out these references: