First-generation antihistamines were developed and marketed to help people with allergies.
Virtually all of them make you sleepy when you take them. So many first-generation antihistamines are actually used in over-the-counter sleep medication.
Another study of these first-generation antihistamines shows many of them have very important actions which it turns out have never been duplicated in newer drugs.
Of course, they will try to sell these old rags as new dresses.
Specifically the antihistamines in the first generation that you may be familiar with include:
Cyproheptadine has one of the chief mechanisms as lowering serotonin in the body.
You probably know that antidepressant drugs are supposedly “selective serotonin reuptake inhibitors” but in reality, serotonin seems to be a stress hormone that causes more harm than good in the human body.
Most serotonin is produced in the gut, and affects the gut.
Serotonin may be responsible for irritable bowel syndrome, Crohn’s disease, and even acid reflux.
Serotonin excess may also be responsible for depression, anxiety, and insomnia.
And IBS.
In this new study, they gave cyproheptadine to kids with irritable bowel syndrome, and
100% of the symptoms disappeared
There were side effects reported. Some of the side effects of cyproheptadine include being sleepy or sedated, and also weight gain.
But on balance, cyproheptadine is very safe.
It’s been tested for decades and decades and is not considered a dangerous drug.
If you have irritable bowel syndrome, or if you have anxiety or even depression, it may be worth considering cyproheptadine.
You can buy it over the counter in the United States
It’s called Periactin.
Or you can get your doctor to prescribe it if he’s ever heard of it. It used to be very common, and it is, in fact, a miracle drug.
It isn’t all that useful for allergies per se, but it is very useful for irritable bowel syndrome, Crohn’s disease, depression, anxiety, maybe even dementia.
Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.
Irritable bowl syndrome (IBS) is an extremely unpleasant gastrointestinal disorder. Many men suffer from it but aren’t sure how to treat it. Luckily, there appears to be something of a miracle cure. Even better, you can get it over the counter. It’s called Periactin.Periactin is an anti-histamine. Its primary ingredient is cypropheptadine.Anti-histamines were initially developed to help people suffering from allergies. Unfortunately, they also tend to make people very sleepy. Some anti-histamines you might be familiar with are diphenhydramine (Benadryl), carbinoxamine (Clistin), clemastine (Tavist), chlorpheniramine (Chlor-Trimeton), and brompheniramine (Dimetane).Though they are primarily used to treat allergies, some anti-histamines have other effects, which have yet to be duplicated in newer drugs. One of these is cyproheptadine.One of the main effects of cyproheptadine is that it lowers serotonin levels in the body. Serotonin is a stress hormone, which affects gut health. Anti-depressants are also known as “selective serotonin reuptake inhibitors” (SSRI) but the fact of the matter is serotonin seems to be a stress hormone that causes more harm than good in the human body.There are theories that excess serotonin may be linked to IBS, anxiety, insomnia, Crohn’s disease, and even acid reflux.In one study, cyproheptadine was given to children suffering from irritable bowel syndrome. One hundred percent of the symptoms disappeared. Most likely this is because it lowered serotonin levels in the kids.There were some side effects, such as weight gain and occasional sleepiness, but on the whole, it’s considered a very safe drug.If you or someone you know is suffering from IBS, get to a drug store and pick up some Periactin. As an anti-histamine it’s not tremendously effective, but it’s proven very handy for IBS, Crohn’s disease, depression, anxiety, and possibly even dementia. This all comes down to its ability to lower serotonin levels.
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