Here’s how…
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Are you taking this? If so you may want to read this very carefully
I’m sure you’ve seen ads for proton pump inhibitors (PPIs).
They’re sold under brand names like Prilosec and Nexium, and they are VERY popular.
People usually take proton pump inhibitors to treat heartburn or acid reflux.
Sometimes they are used to treat ulcers.
Even though you can buy some PPIs over the counter, they have a dark side that most people just don’t know about.
PPIs can attack your kidneys and pull vital minerals out of your body.
What Are Proton Pump Inhibitors (PPIs)?
PPIs are heavily marketed. Which means you’ve probably seen a commercial or ad for them.
They usually are advertised to treat GERD or regular heartburn.
PPIs include heavily marketed and therefore familiar brand-name ‘treatments’ like Prevacid (lansoprazole), Prilosec (omeprazole), and Nexium (esomeprazole). They are ‘given out’ to both prevent and treat ulcers in the duodenum (where most ulcers develop) and the stomach. They also counter the various problems that occur when stomach acid escapes into the esophagus, which — if it happens on a regular basis — is a condition called gastroesophageal reflux disease (GERD). In most head-to-head trials, the PPIs have proved to be superior to the H2 blockers.
They are sold both over the counter and on a doctor’s orders — depending on the type of PPI.
Many people take them without any kind of medical supervision.
PPIs are associated with kidney disease and injury.
Even though many people take these treatments EVERY single day, most people don’t know that they are closely associated with kidney injuries.
PPI use also associated with development of end-stage renal disease
This is a HUGE problem.
If your kidneys fail, the only choice you will have to stay alive is to do dialysis or get a kidney transplant.
Neither of these options are great.
It’s a much better idea to keep the kidneys you have healthy.
Patients who received the following PPIs as “monotherapy” had a significant increase in the frequency of AKI (acute kidney injury) reports: omeprazole (OR 5.8 [3.8, 8.9]), esomeprazole (3.3 [2.2, 5]), pantoprazole (1.8 [1.01, 3.3]), and lansoprazole (10.8 [7.0, 17]). Patients who received rabeprazole as “monotherapy” had an increase in AKI frequency, but it was not significant (1.8 [0.6, 5.3]) (Fig. 3a).
People who use PPIs have a “significant increase” in acute kidney injuries.
It’s crazy that this isn’t better known.
But almost no one knows about it or mentions it.
Electrolyte disturbances are also common.
Another BIG problem with PPIs is that they create electrolyte disturbances.
They suck calcium and magnesium OUT of your system.
All five PPIs were associated with a dramatic increase in hypomagnesemia reports (Fig. 4a, Table 1). Additionally, all the studied PPIs were associated with a significant increase in hypocalcemia reports (Fig. 4b, Table 1). Patients who received the following PPIs had an increase in the frequency of hypokalemia reports: omeprazole, esomeprazole, pantoprazole, and lansoprazole. Patients who received rabeprazole had an increase in hypokalemia frequency, but it was not statistically significant (Fig. 4c, Table 1).
This is a real problem.
Calcium and magnesium are both critical to good health.
So having them disappear from your body isn’t a good thing at all.
Generally speaking, I advise people to stay away from PPIs — especially as a long term maintenance treatment.
The old remedy Pepcid generic, called famotidine, before bedtime, can help a lot of men with this problem and it has some health benefits to it.
But if you’re already taking PPIs, make sure you talk with your doctor about options.
I’m not a doctor and I don’t know your specific situation.
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It seems crazy, but not all treatments are safe, despite doctors giving them out.
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