The real culprit behind anxiety

And it’s the hormone that Big Pharma says is the cure…

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Story-At-a-Glance

Hey, Matt Cook here, and the number of people taking psychiatric treatments for anxiety and depression has skyrocketed over the last few decades…

You probably know that the most common “solution” to this problem is to increase serotonin using SSRI “antidepressants.”

But this new study shows why that may actually be making the problem worse…

Here’s what to do instead if you’re feeling anxious and depressed…

—-Important Message—-

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The real culprit behind anxiety

Many people feel depressed and helpless.

I’ve often written about the problems with the low serotonin theory of depression and helplessness.

Here, we will look at a study that shows that helpless behaviors are very clearly linked to increased serotonin

…again showing that the low serotonin hypothesis of mental illness is completely backward.

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The animal experiments were performed at Mental Health Clinic, Dallas Veterans Affairs Medical Center in Texas. This paper was published in Psychiatry Research.

“Learned helplessness, a behavioral depression caused by exposure to inescapable stress, is considered to be an animal model of human depressive disorder.”

Learned helplessness is a behavioral condition.

It occurs when an animal or person learns to give up in response to repeated stressors that they cannot control or escape.

It is a state in which an individual feels powerless to change a situation, even if there is a way out.

It is associated with self-reported and diagnosed depression and anxiety in humans, and depressive/anxious animal behaviors.

Many see it as a psychological state that you can think or talk your way out of, but there is also a clear biochemical aspect to it.

“Like human depression, learned helplessness has been associated with a defect in serotonergic function, but the nature of this relationship is not entirely clear.”

We don’t have any real-time access to serotonin levels in the human brain. So all of those claims about serotonin levels in the brain are speculative.

There is some real-time analysis of serotonin levels in animals…

But these studies don’t support the serotonin hypothesis – so most people haven’t heard about them.

This study looked at real-time serotonin levels in animal brains.

“We have used in vivo microdialysis brain perfusion to measure serotonin in extracellular space of medial frontal cortex in conscious, freely moving rats.”

Microdialysis brain perfusion is a technique used to monitor the levels of neurotransmitters and other molecules in the extracellular space of the brain.

It involves inserting a small probe into the brain to collect samples of the brain’s extracellular fluid.

Tail-shock stress is commonly used to induce learned helplessness in animal models.

In this procedure, an animal is exposed to an electric shock delivered to its tail, which it cannot escape or avoid.

Repeated exposure to the stressor results in a state of learned helplessness characterized by a passive and inactive response to subsequent stressors.

In other words, after being trained to receive a shock that they can’t escape from, the animals don’t try to escape at a later point when escape is possible.

They have learned to be helpless.

But what’s going on biochemically in the brain?

The researchers didn’t find any relationship between serotonin levels in the brain before the experiment and learned helplessness.

“Basal serotonin levels in rats perfused before exposure to tail-shock stress did not themselves correlate with subsequent learned helplessness behavior.”

The research showed that the more serotonin released during stress, the more likely the animals would suffer from learned helplessness.

We have been told since the 1980s that low brain serotonin levels cause depression, anxiety, and helplessness.

But when we look at what’s happening inside the brain, we find that higher serotonin is tied to learned helplessness.

“However, serotonin release after stress showed a significant increase with helpless behavior.”

The facts shown in these experiments are 180° opposite of what has been claimed for the last 45 years using nothing more than theory and speculation.

All the experimental data I’ve seen shows that brain serotonin seems to cause, rather than cure, psychiatric and behavioral problems.

“These data support the hypothesis that a cortical serotonergic excess is causally related to the development of learned helplessness.”

You should always consult your healthcare practitioner for medical diagnosis and treatment guidance.

—-Important Message—-

This pleasure hormone works 1.8x better than serotonin

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We’re always hearing about how serotonin is the “feel-good” hormone…

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And the best part? It’s fully natural. Your body already makes this hormone on its own.

Discover the natural pleasure hormone that works 1.8 times better than serotonin and how to boost it naturally in the body

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.
In vivo serotonin release and learned helplessnesshttps://pubmed.ncbi.nlm.nih.gov/7991722/